Product Information: Picamilone

Product Information
Providing stimulation and relaxation in one

Sometimes also spelt Pikamilon, Pikamilone or Picamilon, this is a Russian developed nootropic. It is in essence Niacin (vitamin B3) bonded to GABA. Studies have shown that it rapidly crosses the blood-brain barrier, however its effects are much greater and broader than just taking a GABA and Niacin supplement.

Picamilone increases the rate of intracranial and cortex blood circulation and has been cited as a better vasodilator than either Hydergine, Vinpocetine or Xanthinol Nicotinate.

The combination acts as a mild stimulant, yet depresses aggression. This could be the clear actions of Niacin and GABA (after all diazepam's such as Valium® increase or enhance the activity of GABA). But, Picamilone has a tranquilizing effect, without a sedative effect but actually with an element of stimulatory action.

Picamilone is also known to have a mild reversible MAO-A inhibition and thus indicates an anti-depressant quality too.

Other Russian studies with Picamilone show it to improve patients with a mild to moderate memory impairment, emotional, hearing and speech difficulties. Furthermore, Picamilone has reduced migraine or headache pain and aided in alcohol withdrawal. One study showed an improvement for patients suffering from an eye disorder called pigmented retinal abiotrophy (PRA) after 10 days.

Most improvements are noted quickly, often within a week of continuous treatment, and studies show that Picamilone has very low toxicity, with few side effects. Picamilone may be synergistic with other nootropic drugs (such as Lucidril and Piracetam), therefore always remember to reduce overall dosages in order to avoid headaches, nausea and vertigo.

At high dosages, seek your physician's advice if combining with potent vasodilators such as Ginko Biloba, Nicergoline, Vinpocetine or Xanthinol Nicotinate).

Also, due to its mild reversible MAO-A inhibition, at high dosages, without your physician’s advice avoid combination with other MAO-A drugs including Deprenyl and Gerovital-H3 and general anti-depressants (such as Prozac, Paxil and Zoloft etc.).

Dosages are 50mg or 100mg once, twice or maximum three times daily with occasional breaks.

Manufacturers Insert

Composition: Pikamilon, Tri-Calcium Phosphate, Microcrystalline Cellulose.

WHAT IS PICAMILON? Picamilon is a clever combination of GABA and Niacin. By chemically bonding these two vitamins into one compound, a new and unique spectrum of beneficial nootropic (cognitive enhancing) effects are achieved.

WHAT THE STUDIES SAY: Studies show that Picamilon dramatically increases blood flow and circulation within the brain, and achieves results far superior to other nootropic agents such as Hydergine, Ginkgo Biloba etc. In small doses, Picamilon has a tranquilizing action which prevents the negative physiological effects of emotional stress. This tranquilizing influence is also helpful for moderate states of anxiety and depressed negative emotions. Unlike most tranquilizing agents, Picamilon doesn’t have any sedative qualities, making it much more suitable for daily activities. Picamilon provides a tranquilized yet energized state of being.

EFFECTS: The effects of Picamilon are usually felt quickly, with most people noticing impact within an hour. The effects of each dose last for about 4-6 hours. In small doses of 50mg three times per day, Picamilon provides a mild tranquilizing and mood stabilizing effect without sedation. In higher doses of 100mg three times per day, Picamilon provides a stimulating influence that is experienced as an increase in energy and endurance. The cognitive enhancing effects of Picamilon are cumulative and become more evident after several weeks of daily usage. Picamilon has extremely low toxicity, and shows no allergenic or carcinogenic properties. With its unique spectrum of effects, Picamilon may very well be the most amazing dietary supplement discovery of the century!

WARNING: Not for use by children, pregnant or lactating women. If you are under medical supervision, or if you are taking MAO inhibitor medications or any other drugs then consult with your physician before using this product.

Directions: 1 to 2 tablets daily up to three times daily. For maximum absorption take between meals on an empty stomach. For best results use consistently for a period of several weeks as the cognitive enhancing effects are cumulative.

NOTE: These statements have not been evaluated by the food and drug administration. This product is not intended to diagnose, treat, cure or prevent any disease.