Product Information: Xanthinol Nicotinate

Product Information
Xanthinol Nicotinate is a form of Niacin that passes easily through cell membranes; Xanthinol Nicotinate is the most potent form of Niacin available. Niacin is the active part of vitamin B3.

Xanthinol Nicotinate has been shown to increase brain glucose metabolism, improve brain ATP levels and improve brain blood flow (it acts as a vasodilator). As such, Xanthinol Nicotinate has been used to treat short-term memory disorders, mental flagging (i.e. lack of brain energy that compromises vigilance, concentration and attention) and insufficient blood flow to the arteries and the extremities. Furthermore Xanthinol Nicotinate has been clinically shown to improve the reaction speed of the elderly.

Xanthinol Nicotinate (like Niacin) can cause a flushing of the skin and a sense of warmth; it has therefore been suggested that Xanthinol Nicotinate can aid weight control through water loss. However we would suggest that Xanthinol Nicotinate be used for this purpose only prior to exercise or prior to climbing into a hot tub. This is in order to minimize the flushing affects that may be uncomfortable for some people.

Xanthinol Nicotinate can be used as an anti-aging memory support at 1 or 2 tablets (150mg each) three times a day, to a maximum of 12 tablets (1800mg total) prior to a workout or exercise.

Caution: build up to high doses gradually, Xanthinol Nicotinate at high doses can cause blood pressure changes and must therefore be avoided by persons suffering from peptic ulcers, liver problems, severe hypotension, myocardial infarction or other congestive heart problems.

At high dosages, seek your physicians advice if combining with potent vasodilators such as Ginko Biloba, Hydergine, Nicergoline, Picamilone,).

At lower doses some minor side effects such as flushing, nausea, heartburn, itchy skin or vomiting (rare) may present themselves, these normally dissipate with a lower dose or continued use.

Manufacturers Insert

Chemical: Xanthinol Nicotinate

Excipients: 2-ml vials: distilled water, 3-ml vials distilled water, 10-ml vials: distilled water, 150-mg tablets: microgranular cellulose, cornstarch, talc, sodium stearate, polyvinyl pyrrolidone, sodium lauryl sulphate, precipitate silica, 300-mg tablets (“forte”): microgranular cellulose, talc, sodium stearate, cornstarch, polyvinyl pyrrolidone, sodium lauryl sulphate, precipitate silica. 100 ml of drops: p-oxybenzoate of methyl sodium salt, p-oxybenzoate of propyl sodium salt, bitter orange aroma, distilled water. Each delayed-action pill: Eudragit S (acrylic resins), magnesium stearate, talc, sugar, gum arabic, beeswax.

Pharmaceutical Classification: Complamin is a peripheral vasodilator.

Recommendations: Coadjutant in the treatment of peripheral vascular problems.

Contraindications: Hypersensitivity towards the product, cardiac decompensation, acute hemorrhaging, cerebral infarction, acute myocardial infarction (this product is not recommended in the case of coronary insufficiency due to the danger of myocardial infarction), vascular collapse, association with MAO inhibitor or ganglioplegic treatment, gastroduadenal ulcer in it’s evolutionary phase, pregnancy (as a precautionary measure).

Precautions: In the case of prolonged use and high dosage, control the glycaemia of diabetics and closely supervise those patients with serious hyperuricaemia or with serious hepatic insufficiency (transaminase alkaline phosphates). Complamin has no hypotensive action on a long-term basis and therefore does not exclude specific treatment of arterial hypertension. In patients with low pressure, treatment should be strictly controlled. Upon initiating parental treatment, it is advisable to check the patient’s circulation.

Directions for use: Take 1 or 2 tablets (150mg each) three times a day, during or immediately after meals with liquid. Depending on the individual clinical case, the oral dosage may be increased or preceded by treatment with Complamin vials or Complamin infusion, or the two methods may be combined. Complamin drops, take 20 to 30 drops three times daily or before or after meals. 30 drops equals 300mg Complamin.

Unpleasant side effects: A reddening of the skin and a hot feeling have been reported, especially at the beginning of treatment, and these side effects can vary according to the individual. While, in general, such reactions are temporary, it is thought that the patient should be made aware of them should they occur. Cases have also been reported of itching, erythema, and although rarely, arterial hypertension. Consult your physician should you note any unpleasant side effect not mentioned here.

Storage: Discard this product once the expiry date has been passed. Keep out of the reach of children.